Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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Tocris Bioscience™ WQ 1
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Potent and selective σ1 receptor antagonist; active in vivo
| Target | Sigma1 Receptor Antagonists |
|---|---|
| CAS | 1204401-49-9 |
| Purity | 0.98 |
| Chemical Name or Material | 2,3-Dihydro-2-[1-(phenylmethyl)-4-piperidinyl]-4 H-1-benzothiopyran-4-one |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C21H23NOS |
| CAS | 160003-66-7 |
|---|---|
| Molecular Formula | C7 H5 I N2 O3 |
| CAS | 34157-83-0 |
|---|---|
| Molecular Formula | C29H3804 |
Tocris Bioscience™ AS 1842856
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Greener Choice
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Potent and selective Foxo1 inhibitor; orally bioavailable
| CAS | 836620-48-5 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 5-Amino-7-(cyclohexylamino)-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid |
| Molecular Formula | C18H22FN3O3 |
Tocris Bioscience™ T4
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Greener Choice
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Modulator of alternative polyadenylation; inhibits rod photoreceptor gene expression via Nr2e3
| Target | DNA, RNA and Protein Synthesis Compounds |
|---|---|
| CAS | 785708-33-0 |
| Purity | 0.98 |
| Chemical Name or Material | 6,7-Dimethoxy-2-[((4-phenyl-3,6-dihydropyridin-1(2 H)-yl)methyl)]quinazolin-4(3 H)-one |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C22H23N3O3 |
Tocris Bioscience™ LP 99
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Greener Choice
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Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Small and Specialty Supplier Partner
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Selective BRD7 and BRD9 inhibitor (Kd values are 99 and 909 nM, respectively)
| CAS | 1808951-93-0 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | N-[(2R,3S)-2-(4-Chlorophenyl)-1-(1,2-dihydro-1,4-dimethyl-2-oxo-7-quinolinyl)-6-oxo-3-piperidinyl]-2-methyl-1-propanesulfonamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C26H30ClN3O4S |
| Formula Weight | 516.05 |
Tocris Bioscience™ Auxinole
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Auxin antagonist of TIR1/AFB receptors; also OsTIR1 inhibitor in auxin-inducible degron (AID) system
| Target | Molecular Glues |
|---|---|
| CAS | 86445-22-9 |
| Purity | 98% |
| Chemical Name or Material | α-[2-(2,4-Dimethylphenyl)-2-oxoethyl]-1H-indole-3-acetic acid |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C20H19NO3 |
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Thermo Scientific Chemicals Tazarotene
Thermo Scientific Chemicals Tazarotene
CAS: 118292-40-3 Molecular Formula: C21H21NO2S
| CAS | 118292-40-3 |
|---|---|
| Molecular Formula | C21H21NO2S |
Tocris Bioscience™ MOMBA
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Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Selective orthostatic agonist of hFFA2-DREADDs
Tocris Bioscience™ PAG 3'-piperazine
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Functionalized cereblon ligand for PROTAC development
| Shipping Condition | No special requirements |
|---|---|
| CAS | 481-49-2 |
| Color | White to Light-yellow to Beige |
| Purity | ≥94% |
| Physical Form | Crystalline Powder |
| Health Hazard 1 | Exclamation mark |
| Chemical Name or Material | Cepharanthine |
| Recommended Storage | Refrigerator +4°C |
| Molecular Formula | C37 H38 N2 O6 |
| Product Line | Life science |
Tocris Bioscience™ Ambrisentan
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Greener Choice
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Selective ETA antagonist
| CAS | 85650-56-2 |
|---|---|
| Molecular Formula | C17H16ClNO·C4H4O4 |